a case of tuberous sclerosis with ocular involvement

purpose: to report multiple astrocytic hamartomas in a patient with tuberous sclerosis (ts). patient and findings: a 16-year-old girl with ts without any ocular complaint was referred for ophthalmologic examination. she had papular rash on her face and other skin lesions elsewhere in the body which were specific for ts. multiple well-circumscribed elevated lesions characteristic of astrocytic hamartoma were seen in the retina of both eyes. two larger nodular and calcified masses, one in inferotemporal retina of the left eye and another in superotemporal retina of the right eye were also detected. one of these lesions was located in far periphery. conclusion: one of the retinal masses in our patient was located in the far periphery of the retina which is in contrast to previous reports that mention a maximum of 2 disc diameter distance from the optic disc for such lesions. because of high probability of eye involvement, all cases of ts should undergo a thorough ocular examination.